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Engineered FnCas12a with Enhanced Activity Through Directional Evolution in Human Cells

Xiexie Liu,Xiaoyu Liu,Chenchen Zhou,Jineng Lv,Xiubin He,Yuanyuan Liu,Haihua Xie,Bang Wang,Xiujuan Lv,Lianchao Tang, Mingchun Li,Changbao Liu,Junzhao Zhao,Yong Liu,Zongming Song,Feng Gu

Journal of Biological Chemistry（2021）

Cited 15|Views27
Key words
FnCas12a,activity,PAM,variant,RS1
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