Pathophysiological Insights into Atrial Fibrillation: Revisiting the Electrophysiological Substrate, Anatomical Substrate, and Possible Insights from Proteomics
CARDIOVASCULAR RESEARCH（2021）
University of Liverpool
Abstract
profiling of blood plasma, atrial tissue biopsy, and retrieved thrombi offers immense potential for biomarker discovery, gaining mechanistic insights into atrial electrophysiological and structural remodelling, and thrombogenesis, which in turn can provide novel insights into AF management and anticoagulation therapy.
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Key words
Atrial fibrillation,Fibrosis,Thrombosis,Stroke,Pulmonary vein
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