Primary Human Hepatocyte Spheroid Model As a 3D in Vitro Platform for Metabolism Studies

Kajsa P. Kanebratt,Annika Janefeldt,Liisa Vilen,Anna Vildhede,Kristin Samuelsson, Lucas Milton,Anders Bjorkbom, Marie Persson,Carina Leandersson,Tommy B. Andersson,Constanze Hilgendorf

JOURNAL OF PHARMACEUTICAL SCIENCES（2021）

引用 42|浏览49

关键词

Cytochrome P450 (CYP),Hepatic metabolism,Hepatocyte(s),In vitro model(s),Metabolic clearance,Absorption,Distribution,Metabolism and Excretion (ADME),Cell culture

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