Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced in Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.
Toxicological Sciences（2020）
Key words
reactive intermediate,alternatives to animal testing,drug-induced liver injury (DILI),liver,in vitro models,hepatotoxicity,gene expression,toxicogenomics,predictive toxicology,risk assessment
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