RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies
Benjamin J. Solomon,Lavinia Tan,Jessica J. Lin,Stephen Q. Wong,Sebastian Hollizeck,Kevin Ebata,Brian B. Tuch,Satoshi Yoda,Justin F. Gainor,Lecia V. Sequist,Geoffrey R. Oxnard,Oliver Gautschi,Alexander Drilon,Vivek Subbiah,Christine Khoo,Edward Y. Zhu,Michele Nguyen,Dahlia Henry,Kevin R. Condroski,Gabrielle R. Kolakowski,Eliana Gomez,Joshua Ballard,Andrew T. Metcalf,James F. Blake,Sarah-Jane Dawson,Wayne Blosser,Louis F. Stancato,Barbara J. Brandhuber,Steve Andrews,Bruce G. Robinson,S. Michael Rothenberg Journal of Thoracic Oncology(2020)
Key words
RET fusion,RET mutation,Acquired resistance,Multikinase inhibitor,Selective tyrosine kinase inhibitor
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