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Discovery and Characterization of the Antimetabolite Action of Thioacetamide-Linked 1,2,3-Triazoles As Disruptors of Cysteine Biosynthesis in Gram-Negative Bacteria

Miranda J. Wallace,Suresh Dharuman,Dinesh M. Fernando,Stephanie M. Reeve,Clifford T. Gee,Jiangwei Yao,Elizabeth C. Griffith,Gregory A. Phelps,William C. Wright,John M. Elmore,Robin B. Lee,Taosheng Chen,Richard E. Lee

ACS INFECTIOUS DISEASES（2020）

引用 17|浏览22
关键词
antimetabolite,Gram-negative drug discovery,antifolate,1,2,3-triazole,cysteine synthase,high-throughput screen
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