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Exploring Targeted Degradation Strategy for Oncogenic KRASG12C.

Mei Zeng,Yuan Xiong,Nozhat Safaee,Radosaw P. Nowak,Katherine A. Donovan,Christine J. Yuan,Behnam Nabet,Thomas W. Gero,Frederic Feru,Lianbo Li,Sudershan Gondi, Lincoln J. Ombelets,Chunshan Quan,Pasi A. Janne,Milka Kostic,David A. Scott,Kenneth D. Westover,Eric S. Fischer,Nathanael S. Gray

Cell chemical biology（2020）

引用 218|浏览98
关键词
KRASG12C,PROTAC,CRBN,targeted protein degradation,ubiquitination,degrader,caner
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