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Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction.

Sifan Chen,Ayana Henderson,Michael C. Petriello,Kymberleigh A. Romano,Mary Gearing,Ji Miao,Mareike Schell,Walter J. Sandoval-Espinola,Jiahui Tao,Bingdong Sha,Mark Graham,Rosanne Crooke,Andre Kleinridders,Emily P. Balskus,Federico E. Rey,Andrew J. Morris,Sudha B. Biddinger

CELL METABOLISM（2019）

Cited 286|Views54
Key words
diabetes,insulin signaling,endoplasmic reticulum stress,FoxO1,trimethylamine N-oxide,metabolomics,EIF2AK3,PERK
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