Identification of CNS-Penetrant Aryl Sulfonamides As Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy.
Thilo Focken,Kristen Burford,Michael E. Grimwood,Alla Zenova,Jean-Christophe Andrez,Wei Gong,Michael Wilson,Matt Taron,Shannon Decker,Verner Lofstrand,Sultan Chowdhury,Noah Shuart,Sophia Lin,Samuel J. Goodchild,Clint Young,Maegan Soriano,Parisa K. Tari,Matthew Waldbrook,Karen Nelkenbrecher,Rainbow Kwan,Andrea Lindgren,Gina de Boer,Stephanie Lee,Luis Sojo,Robert J. DeVita,Charles J. Cohen,Steven S. Wesolowski,J. P. Johnson,Christoph M. Dehnhardt,James R. Empfield Journal of Medicinal Chemistry（2019）
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