Soluble Aggregates Present in Cerebrospinal Fluid Change in Size and Mechanism of Toxicity During Alzheimer’s Disease Progression

Suman De,Daniel R. Whiten,Francesco S. Ruggeri,Craig Hughes,Margarida Rodrigues,Dimitrios I. Sideris,Christopher G. Taylor,Francesco A. Aprile,Serge Muyldermans,Tuomas P. J. Knowles,Michele Vendruscolo,Clare Bryant,Kaj Blennow,Ingmar Skoog,Silke Kern,Henrik Zetterberg,David Klenerman

Acta Neuropathologica Communications（2019）

Cited 75|Views70

Key words

Alzheimer’s disease,Mild cognitive impairment,Cerebrospinal fluid,Protein aggregation,Structure-function relation,Super-resolution imaging,Disease mechanism

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