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FUS Pathology in ALS is Linked to Alterations in Multiple ALS-associated Proteins and Rescued by Drugs Stimulating Autophagy

Lara Marrone,Hannes C. A. Drexler,Jie Wang,Priyanka Tripathi,Tania Distler, Patrick Heisterkamp,Eric Nathaniel Anderson,Sukhleen Kour,Anastasia Moraiti,Shovamayee Maharana,Rajat Bhatnagar,T. Grant Belgard,Vadreenath Tripathy,Norman Kalmbach,Zohreh Hosseinzadeh,Valeria Crippa,Masin Abo-Rady,Florian Wegner,Angelo Poletti,Dirk Troost,Eleonora Aronica,Volker Busskamp,Joachim Weis,Udai Bhan Pandey,Anthony A. Hyman,Simon Alberti,Anand Goswami,Jared Sterneckert

Acta Neuropathologica（2019）

Cited 91|Views33
Key words
Amyotrophic lateral sclerosis,FUS,Induced pluripotent stem cells,RNA-binding proteins,Phase transition,Protein homeostasis
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