Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds

Andreas Luxenburger,Dorian Schmidt,Chiara Ianes,Christian Pichlo,Marc Krueger,Thorsten von Drathen,Elena Brunstein,Graeme J. Gainsford,Ulrich Baumann,Uwe Knippschild,Christian Peifer

Molecules（2019）

引用 11|浏览27

关键词

protein kinase CK1,formerly known as casein kinase 1,chiral kinase inhibitors,iminoribitol,ribose pocket,3,4-diaryl-isoxazole,Pictet-Spengler cyclization

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