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Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

Guoqiang Yi,Albertus T. J. Wierenga,Francesca Petraglia, Pankaj Narang,Eva M. Janssen-Megens,Amit Mandoli,Angelika Merkel,Kim Berentsen,Bowon Kim,Filomena Matarese,Abhishek A. Singh,Ehsan Habibi,Koen H. M. Prange,Andre B. Mulder,Joop H. Jansen,Laura Clarke,Simon Heath,Bert A. van der Reijden,Paul Flicek,Marie-Laure Yaspo,Ivo Gut,Christoph Bock,Jan Jacob Schuringa,Lucia Altucci,Edo Vellenga,Hendrik G. Stunnenberg,Joost H. A. Martens

Cell Reports（2019）

Cited 39|Views122
Key words
acute myeloid leukemia,AML,histone marks,chromatin states,DNA accessibility,stemness,epigenome,transcriptome
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