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Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

Sema Kurtulus,Asaf Madi,Giulia Escobar,Max Klapholz,Jackson Nyman,Elena Christian,Mathias Pawlak,Danielle Dionne,Junrong Xia,Orit Rozenblatt-Rosen,Vijay K. Kuchroo,Aviv Regev,Ana C. Anderson

Immunity（2019）

引用 460|浏览65
关键词
CD8+ T cell,cancer,single-cell,dysfunction,exhaustion,memory,checkpoint blockade,immunotherapy,PD-1,Tim-3
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