Design, Synthesis and Evaluation of MCH Receptor 1 Antagonists—part II: Optimization of Pyridazines Toward Reduced Phospholipidosis and Herg Inhibition
Bioorganic & Medicinal Chemistry Letters(2015)
Key words
Melanin-concentrating hormone (MCH),MCH-R1 antagonists,Pyridazine chemistry,Phospholipidosis,hERG inhibition
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