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Optimizing a Weakly Binding Fragment into a Potent RORγt Inverse Agonist with Efficacy in an in Vivo Inflammation Model.

David A. Carcache,Anna Vulpetti,Joerg Kallen,Henri Mattes,David Orain,Rowan Stringer,Eric Vangrevelinghe,Romain M. Wolf,Klemens Kaupmann,Johannes Ottl,Janet Dawson,Nigel G. Cooke,Klemens Hoegenauer,Andreas Billich,Juergen Wagner,Christine Guntermann,Samuel Hintermann

Journal of Medicinal Chemistry（2018）

Cited 27|Views51
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