Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease

Karthickeyan Chella Krishnan,Zeyneb Kurt,Rio Barrere-Cain,Simon Sabir, Aditi Das,Raquel Floyd,Laurent Vergnes,Yuqi Zhao,Nam Che,Sarada Charugundla,Hannah Qi,Zhiqiang Zhou,Yonghong Meng,Calvin Pan,Marcus M. Seldin,Frode Norheim,Simon Hui,Karen Reue,Aldons J. Lusis,Xia Yang

SSRN Electronic Journal（2018）

Cited 114|Views55

Key words

non-alcoholic fatty liver disease,multi-omics integration,network modeling,key driver genes,mitochondrial dysfunction,oxidative phosphorylation,glycolysis,systems biology,integrative genomics,mouse diversity panel

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