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Discovery of 3-Alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-carbonitriles As Selective, Orally Bioavailable CHK1 Inhibitors

Michael Lainchbury,Thomas P. Matthews,Tatiana McHardy,Kathy J. Boxall,Michael I. Walton,Paul D. Eve,Angela Hayes,Melanie R. Valenti,Alexis K. de Haven Brandon,Gary Box,G. Wynne Aherne,John C. Reader,Florence I. Raynaud,Suzanne A. Eccles,Michelle D. Garrett,Ian Collins

JOURNAL OF MEDICINAL CHEMISTRY（2012）

Cited 34|Views19

Key words

Cancer Therapy,Tumor Suppression

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