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A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells

Meromit Singer,Chao Wang,Le Cong,Nemanja D. Marjanovic,Monika S. Kowalczyk,Huiyuan Zhang,Jackson Nyman,Kaori Sakuishi,Sema Kurtulus,David Gennert,Junrong Xia,John Y. H. Kwon,James Nevin,Rebecca H. Herbst,Itai Yanai,Orit Rozenblatt-Rosen,Vijay K. Kuchroo,Aviv Regev,Ana C. Anderson

Cell（2016）

Cited 400|Views95
Key words
CD8,T cell,exhaustion,dysfunction,cancer,single-cell,CRISPR/Cas9,Gata-3,metallothioneins,zinc,TILs,tumor
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