Suppression of c- myc expression and c-Myc function in response to sustained DNA damage in MCF-7 breast tumor cells 3 3 Abbreviations: ODC, ornithine decarboxylase; VM-26 (teniposide), 4′-demethylepipodophyllotoxin-4-(4,6- O-thenylidene-β-d-glucopyranoside); pRb, retinoblastoma protein; m-AMSA, amsacrine; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; and FBS, fetal bovine serum.
Biochemical Pharmacology(2001)
Key words
ionizing radiation,signal transduction pathway,terminal deoxynucleotidyl transferase,dna damage,ornithine decarboxylase,cell morphology,glyceraldehyde 3 phosphate dehydrogenase,cell cycle,cell death
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