Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other*

Chutikarn Butkinaree,Maryssa Canuel,Rachid Essalmani,Steve Poirier,Suzanne Benjannet,Marie-Claude Asselin,Anna Roubtsova,Josee Hamelin,Jadwiga Marcinkiewicz,Ann Chamberland,Johann Guillemot,Gaetan Mayer,Sangram S. Sisodia,Yves Jacob,Annik Prat,Nabil G. Seidah

Journal of Biological Chemistry（2015）

引用 46|浏览74

关键词

cardiovascular disease,dyslipidemia,lipoprotein metabolism,low-density lipoprotein (LDL),proprotein convertase subtilisin/kexin type 9 (PCSK9),APLP2,Sortilin (SORT1),low-density lipoprotein receptor (LDLR) degradation

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