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A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo.

Alan G Olivero,Charles Eigenbrot,Richard Goldsmith,Kirk Robarge,Dean R Artis,John Flygare,Thomas Rawson,Daniel P Sutherlin,Saloumeh Kadkhodayan,Maureen Beresini,Linda O Elliott,Geralyn G DeGuzman,David W Banner,Mark Ultsch,Ulla Marzec,Stephen R Hanson,Canio Refino,Stuart Bunting,Daniel Kirchhofer

The Journal of biological chemistry（2005）

引用 48|浏览25
关键词
factor viia binds,attenuates thrombus conformation,slow binding inhibitor
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