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Conformationally Constrained Farnesoid X Receptor (FXR) Agonists: Alternative Replacements of the Stilbene.

Adwoa Akwabi-Ameyaw,Justin A. Caravella,Lihong Chen,Katrina L. Creech,David N. Deaton,Kevin P. Madauss,Harry B. Marr,Aaron B. Miller,Frank Navas,Derek J. Parks,Paul K. Spearing,Dan Todd,Shawn P. Williams,Bruce Wisely

Bioorganic & Medicinal Chemistry Letters（2011）

引用 33|浏览20
关键词
Farnesoid X receptor,FXR,Nuclear receptor modulator,FXR X-ray co-crystal structure,GW 4064,GSK8062,GSK2324,Bile acid receptor,NR1H4
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