Under the Gerontology Research Programme, he is the Principal Investigator of the Singapore Longitudinal Ageing Studies (SLAS), a population-based cohort follow-up study of 6,000 older Singaporeans, which focus on the themes of dementia, depression, frailty and successful ageing.

His current research interests include the role of insulin resistance and metabolic syndrome in dementia, multisystem biological and multi-domain biopsychosocial characterisation of frailty and successful ageing, and population-based and clinical interventions.

Prof Ng has published over 300 research papers in peer-reviewed journals and presented 150 papers in scientific conferences and meetings on dementia, depression, physical disability, frailty and successful ageing. He is a member of the expert panel of American Association of Retired Persons (AARP) Global Council on Brain Health, and the Editorial Boards of a number of scientific journals including Dementia and Geriatric Cognitive Disorders, Journal of Alzheimer’s Disease, Postgraduate Medicine, Current Translational Geriatrics & Experimental Gerontology Reports.

Over the years, he has provided consultancy services and was on the advisory panels and scientific working groups of a number of government and non-governmental organizations, and has conducted numerous training courses, public lectures and talks on gerontological topics at local and international meetings.