M.Sofiev has worked in the field of atmospheric physics and chemistry concentrating on development and application of the Eulerian and Lagrangian air pollution models for meso-to-global scales in the troposphere and the stratosphere, as well as operational air quality and accidental release dispersion forecasting. He is the coordinator of development of System for Integrasted modeLling of Atmospheric coMposition (SILAM). Specific areas of interest include model development, verification and comparison with measurements, data assimilation, statistical methodology for model validation, analysis of the measurement data, inverse and adjoint dispersion modeling, computer experiments, etc. Compounds of interest are: acidifying and toxic pollutants, ozone, radioactive and biological species, atmospheric aerosols.