Thomas Simon

基本信息

Career Trajectory

Bio

My research work mainly focuses on the identification of molecular targets for the development of novel therapeutic options against cancers of the central nervous system (including glioblastoma and brain metastasis). I have a great interest for interactions between cancer cells and their direct microenvironment through extracellular vesicles.

Research Interests

Papers共 167 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Utility of Genome Sequencing and Group-Enrichment to Support Splice Variant Interpretation in Marfan Syndrome

Susan Walker,David J Bunyan,Huw B Thomas,Yesim Kesim,Christopher J Kershaw,John Holloway,Htoo Wai, Michael Day, Cassandra L Smith,Gareth Hawkes,Andrew R Wood,Michael N Weedon, Ed Blair,Stephanie L Curtis, Catherine Fielden,Julie Evans,Rebecca Whittington,Sarah F Smithson,Helen Cox,Paul Clift,Meriel McEntagart,Matina Prapa, Suzanne Alsters, Deborah Morris-Rosendahl,John Dean,Patrick J Morrison,Abhijit Dixit,Ajoy Sarkar,Katrina Prescott, Leila Amel Riazat Kesh, Riya Tharakan,Claire Turner,Sian Ellard,Charles Shaw-Smith,James Fasham,Virginia Clowes,Simon Holden, Suresh Somarathi,Catherine Mercer,Ian Berry,Raymond T O'Keefe,Siddharth Banka,Diana Baralle,N Simon Thomas,Emma L Baple,Jenny C Taylor,Alistair T Pagnamenta

Genetics in medicine official journal of the American College of Medical Geneticspp.101477-101477, (2025)

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Uplift of Genetic Diagnosis of Rare Respiratory Disease Using Airway Epithelium Transcriptome Analysis

Jelmer Legebeke,Gabrielle Wheway, Lee Baker,Htoo A. Wai,Woolf T. Walker,N. Simon Thomas,Janice Coles,Claire L. Jackson,John W. Holloway,Jane S. Lucas,Diana Baralle

Human molecular geneticsno. 2 (2025): 148-160

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Pathogenic De Novo Variants in PPP2R5C Cause a Neurodevelopmental Disorder Within the Houge-Janssens Syndrome Spectrum

Iris Verbinnen,Sofia Douzgou Houge,Tzung-Chien Hsieh,Hellen Lesmann, Aron Kirchhoff,David Geneviève,Elise Brimble,Lisa Lenaerts,Dorien Haesen, Rebecca J Levy,Julien Thevenon,Laurence Faivre,Elysa Marco,Jessica X Chong,Mike Bamshad,Karynne Patterson,Ghayda M Mirzaa,Kimberly Foss,William Dobyns,Susan M White,Lynn Pais,Emily O'Heir,Raphaela Itzikowitz,Kirsten A Donald,Celia Van der Merwe,Alessandro Mussa, Raffaela Cervini,Elisa Giorgio,Tony Roscioli,Kerith-Rae Dias,Carey-Anne Evans,Natasha J Brown,Anna Ruiz,Juan Pablo Trujillo Quintero,Rachel Rabin,John Pappas, Hai Yuan,Katherine Lachlan,Simon Thomas, Anita Devlin,Michael Wright, Richard Martin, Joanna Karwowska,Renata Posmyk,Nicolas Chatron,Zornitza Stark, Oliver Heath,Martin Delatycki,Rebecca Buchert,Georg-Christoph Korenke,Keri Ramsey,Vinodh Narayanan,Dorothy K Grange,Judith L Weisenberg,Tobias B Haack,Stephanie Karch,Patricia Kipkemoi, Moses Mangi,Karen G C B Bindels de Heus,Marie-Claire Y de Wit,Tahsin Stefan Barakat,Derek Lim,Géraldine Van Winckel,Rebecca C Spillmann,Vandana Shashi,Maureen Jacob, Antonia M Stehr,Undiagnosed Diseases Network,Peter Krawitz,Gunnar Douzgos Houge,Veerle Janssens

American journal of human geneticsno. 3 (2025): 554-571

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Secondary (additional) Findings from the 100,000 Genomes Project: Disease Manifestation, Health Care Outcomes, and Costs of Disclosure

Joshua Nolan,James Buchanan,John Taylor, Joao Almeida,Tina Bedenham,Edward Blair,Suzanne Broadgate,Samantha Butler, Angela Cazeaux,Judith Craft,Treena Cranston,Gillian Crawford, Jamie Forrest,Jessica Gabriel, Elaine George, Donna Gillen, Ash Haeger,Jillian Hastings Ward,Lara Hawkes, Claire Hodgkiss,Jonathan Hoffman,Alan Jones,Fredrik Karpe,Dalia Kasperaviciute, Erika Kovacs,Sarah Leigh,Elizabeth Limb, Anjali Lloyd-Jani,Javier Lopez,Anneke Lucassen, Carlos McFarlane, Anthony W. O'Reurke, Emily Pond,Catherine Sherman,Helen Stewart,Ellen Thomas,Simon Thomas,Tessy Thomas,Kate Thomson, Hannah Wakelin,Susan Walker,Melanie Watson,Eleanor Williams,Elizabeth Ormondroyd

GENETICS IN MEDICINE（2024）

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First Report of RNA Editing in Human Retina - a Process Central to Photoreceptor Health, and a Risk Factor for Both AMD and Rarer Macular Degeneration

Brendan Robert E. Ansell,Roberto Bonelli,Simon N. Thomas, Aravind Manda,Rinki Ratnapriya,Michele Pinelli,Anand Swaroop, Diego diBernardo,Sandro Banfi,Melanie Bahlo

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 7 (2024)

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Single Cell Sequencing Reveals Cancer Associated Fibroblast Heterogeneity at the Core of the Tumor Microenvironment in Brain Metastasis

Thomas Simon,David N. Buckley,Ben Y. Tew,Matthew Salomon, Zeyi Yang,Gerald C. Gooden,Steven A. Toms,Gabriel Zada,Bodour Salhia

CANCER RESEARCHno. 6 (2024)

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A Gene Pathogenicity Tool 'genepy' Identifies Missed Biallelic Diagnoses in the 100,000 Genomes Project

Eleanor G. Seaby,Gary Leggatt,Guo Cheng,N. Simon Thomas,James J. Ashton,Imogen Stafford,Diana Baralle,Heidi L. Rehm,Anne O. ' Donnell-Luria,Sarah Ennis

Genetics in medicine official journal of the American College of Medical Geneticsno. 4 (2024): 101073-101073

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Analyses of 1,236 Genotyped Primary Ciliary Dyskinesia Individuals Identify Regional Clusters of Distinct DNA Variants and Significant Genotype-Phenotype Correlations

Johanna Raidt,Sarah Riepenhausen,Petra Pennekamp,Heike Olbrich,Israel Amirav,Rodrigo A Athanazio,Micha Aviram,Juan E Balinotti, Ophir Bar-On,Sebastian FN Bode,Mieke Boon,Melissa Borrelli,Siobhan B Carr,Suzanne Crowley,Eleonora Dehlink, Sandra Diepenhorst,Peter Durdik,Bernd Dworniczak,Nagehan Emiralioğlu,Ela Erdem,Rossella Fonnesu,Serena Gracci,Jörg Große-Onnebrink, Karolina Gwozdziewicz,Eric G Haarman,Christine R Hansen,Claire Hogg,Mathias G Holgersen,Eitan Kerem,Robert W Körner,Karsten Kötz,Panayiotis Kouis,Michael R Loebinger,Natalie Lorent,Jane S Lucas,Debora Maj,Marcus A Mall,June K Marthin,Vendula Martinu,Henryk Mazurek,Hannah M Mitchison,Tabea Nöthe-Menchen,Ugur Özçelik,Massimo Pifferi,Andrzej Pogorzelski,Felix C Ringshausen,Jobst F Roehmel,Sandra Rovira-Amigo,Nisreen Rumman,Anne Schlegtendal,Amelia Shoemark,Synne Sperstad Kennelly,Ben O Staar,Sivagurunathan Sutharsan,Simon Thomas,Nicola Ullmann,Julian Varghese,Sandra von Hardenberg,Woolf T Walker,Martin Wetzke,Michal Witt,Panayiotis Yiallouros,Anna Zschocke,Ewa Ziętkiewicz,Kim G Nielsen,Heymut Omran

European Respiratory Journal (2024)

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The International Registry for Primary Ciliary Dyskinesia Reveals Regional Variation of Genotypes and Significant Genotype-Phenotype Correlations

Johanna Raidt,Sarah Riepenhausen,Israel Amirav,Rodrigo A. Athanazio,Micha Aviram,Juan E. Balinotti, Ophir Bar-On,Sebastian Fn Bode,Mieke Boon,Melissa Borrelli,Siobhan B. Carr,Suzanne Crowley,Eleonora Dehlink, Sandra Diepenhorst,Peter Durdik,Bernd Dworniczak,Nagehan Emiralioglu,Ela Erdem,Rossella Fonnesu,Serena Gracci,Joerg Grosse-Onnebrink, Karolina Gwozdziewicz,Eric G. Haarman,Christine R. Hansen,Claire Hogg,Mathias G. Holgersen,Varghese Julian,Eitan Kerem,Robert W. Korner,Karsten Kotz,Panayiotis Kouis,Michael R. Loebinger,Natalie Lorent,Jane S. Lucas,Debora Maj,Marcus A. Mall,June K. Marthin,Vendula Martinu,Henryk Mazurek,Hannah M. Mitchison,Tabea Noethe-Menchen,Heike Olbrich,Ugur Ozcelik,Petra Pennekamp,Massimo Pifferi,Andrzej Pogorzelski,Felix C. Ringshausen,Jobst F. Roehmel,Sandra Rovira-Amigo,Nisreen Rumman,Anne Schlegtendal,Amelia Shoemark,Synne Sperstad Kennelly,Ben Staar,Sivagurunathan Sutharsan,Simon Thomas,Nicola Ullmann,Sandra Von Hardenberg,Woolf Walker,Martin Wetzke,Michal Witt,Panayiotis Yiallouros,Ewa Zietkiewicz,Kim G. Nielsen,Heymut Omran

EUROPEAN RESPIRATORY JOURNAL (2024)

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Additional Findings in the 100,000 Genomes Project: Disease Manifestation and Healthcare Utilisation (SAFE Study)

Joshua Nolan,James Buchanan, Jamie Forrest,Anneke Lucassen, Sam Butler, Angela Cazeaux,Gill Crawford, Elaine George, Donna Gillen,Jillian Hastings-Ward,Lara Hawkes, Jon Hoffman,Alan Jones,Fredrik Karpe, Erika Kovacs, Carlos McFarlane,Helen Stewart,Catherine Sherman,John Taylor,Simon Thomas,Tessy Thomas, Hannah Wakelin,Elizabeth Ormondroyd

EUROPEAN JOURNAL OF HUMAN GENETICS (2024): 696-697

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Associate Research

Papers共 167 篇Author StatisticsCo-AuthorSimilar Experts