Dr. Graham is a medical physicist and biomedical engineer with diverse interests in the development of MRI technology for clinical applications involving the brain. In the past, he has conducted numerous studies aimed at improving the understanding of the biophysical properties of biological tissue that affect MRI signal contrast; improving the method and application of functional Magnetic Resonance Imaging (fMRI) of brain activity in healthy individuals as well as patients suffering from stroke, Alzheimer's Disease, mild cognitive impairment, brain cancer, and traumatic brain injury; general development and optimization of MRI methods; and detailed numerical simulations, computational methods, and MRI hardware development towards improved use of MRI and associated medical devices (e.g. deep brain stimulators). He has a lengthy track record of successfully leading collaborative research grants and projects. Several ongoing research projects are described below.