Rolf has made a major contribution to methods for the automatic annotation of proteins, making it possible to add relevant information to proteome sets for entire organisms. He has spearheaded the development of standards for proteomics data, and his teams have maintained major collections of protein identifications from proteomics experiments (PRIDE) and molecular interactions (IntAct). He also led EMBL-EBI’s contribution to the Gene Ontology, was Director of Open Targets, and is now leading the efforts of EMBL-EBI around the European COVID-19 Data Platform.