Professor Ramesh Rajan's research is predicated on the over-riding hypothesis that a huge part of our internal lives and our interactions with the world are guided by our senses, by what we hear, see, touch, smell, taste and our other senses.

Using this overarching theme, he studies sensory processing in the brain to understand how brain disorders affect the way in which we receive and process information about the world, to shape and guide our internal lives and our responses to the world and how the many cognitive, motor, memory and emotional deficits in brain disorders may flow from disordered sensory processing that distorts our world view and our interactions with self and others.

He studies models of traumatic brain injury and the processing of sensory information, as well as how brain alterations in conditions like Huntington's Disease, Multiple Sclerosis, Autism Spectrum Disorders, and Parkinson's Disease, affect the ability to understand our most powerful communication tool, namely speech, in noisy backgrounds.