His areas of clinical expertise include chronic fatigue syndrome and other disorders characterized by fatigue and orthostatic intolerance. Dr. Rowe and his colleagues were the first to describe the relationship between chronic fatigue syndrome (CFS) and treatable orthostatic intolerance syndromes, as well as the association between Ehlers-Danlos syndrome and CFS.

In 2014, Dr. Rowe received the research award from the International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (IACFS/ME) for his clinical and scientific work on chronic fatigue syndrome and related disorders. He is a member of the research advisory council for Solve ME/CFS. He is also a member of the American Pediatric Society, the Society for Pediatric Research, the Canadian Pediatric Society, and the American Academy of Pediatrics.