As a creative bioinformatician with training in molecular biology and pharmaceutical sciences, I excel in the translation of biomedical problems into computational solutions in the area of personalized medicine. I have a strong track record in methodology and technology development, both in the laboratory and at the computer. My analytical skills allow me to quickly trace hidden treasures and potential flaws in proposed solutions to complex problems. Members of my team appreciate my constructive criticism, dedication, ambition and care for science and my attention for their personal lives and capacity development. To see PhD students and postdocs grow to independence is among the most rewarding aspects of my current work.

I am dedicated to the advancement of personalized medicine approaches for rare diseases by integrative use of -omics and clinical data. I am the coordinator of the European SIMPATHIC project aiming for acceleration of drug repurposing for rare neurological, neurometabolic and neuromuscular disorders. I am leading the Radboudumc program on neuromuscular disorders and has myotonic dystrophy as disease focus. Since data from rare disease patient is scarce and fragmented, I dedicate a significant amount of time in making data Findable, Accessible, Interoperable and Reusable and on developing infrastructure for the federated analysis of personal data such as advocated by the Personal Health Train initiative. To this end, I am directing the data analysis, integration and stewardship pillar within the Netherlands X-omics initiative; I am actively contributing to other data infrastructures such as HealthyData (workpackage leader “unlocking” data), HealthRI (national; tactical lead for the Nijmegen region), and international infrastructures such as European Rare Diseases Research Alliance (ERDERA), EURO-NMD registry, EATRIS and ELIXIR. I am FAIR and Open Science ambassador in Radboud university medical center and member of the steeringboard of the Dutch regieorgaan OpenScience.NL.