Dr. Shah is a physician scientist who serves as the Head of the Hematologic Malignancies Section of the Pediatric Oncology Branch. Her research focuses on the development of targeted immunotherapy approaches to treat high-risk blood cancers, such as leukemia and lymphoma, in children, adolescents, and young adults. She is also interested in the prevention and treatment of relapsed disease after allogeneic hematopoietic stem cell transplantation. Her clinical trials focus on exploring and improving chimeric antigen receptor (CAR) T-cell based therapies and other antibody-based therapies to target surface proteins found on leukemia cells to improve outcomes for patients with blood cancers that do not respond to chemotherapy. Her research aims to reduce the toxicities and late effects of these therapies. Dr. Shah also served as the NCI Fellowship Program director for the joint Johns Hopkins Hospital-National Cancer Institute Pediatric Hematology-Oncology Fellowship Program and is an alumnus of the program. Based on her ongoing efforts in myeloid malignancies, Dr. Shah is the co-chair of the Myeloid Malignancies Program Steering Committee and also an adjunct investigator in the Immune Deficiency Cell Therapy Program.