My research focuses on the application of genetic epidemiology to the dissection of potentially causal relationships between modifiable risk factors and complex health outcomes. My programmatic work specifically focuses on understanding body mass index (BMI) as a risk factor - using a variety of study designs and molecular phenotyping to examine pathways to disease and intervention effects. I lead work applying these methods to questions on the aetiology of cancer, cardiovascular health and the role of the environment in cardiometabolic health.