Maud de Dieuleveult

Current research interest: Global consequences of pre-replication complex mutations on DNA replication, cell proliferation, epigenome modification and chromatin organization in Meier-Gorlin syndrome cases. Previous projects: 2015-2019: USP9X roles and contribution on mouse embryonic stem cells phenotype and metabolism. 2011-2014: LSH/Hells and hydroxymethylation in mouse embryonic stem cells and fibroblasts. 2006-2010: Implication of the Chd remodelers in pluripotency networks of stem cells. Techniques: Chromatin immunoprecipitation (ChIP-seq), Protein and complexes pull-down, Label free mass spectrometry analysis, Dot-blot assays, transcriptomic analysis, ES cell culture and differentiation, qPCR, Western-blot..