Kim Brouwer

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职业迁徙

个人简介

Research Mechanisms of hepatic uptake, translocation and biliary excretion Drug transport Pharmacokinetics Aberrant gastrointestinal drug absorption phenomena

研究兴趣

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Correction to "nanoparticle Drug Delivery Can Reduce the Hepatotoxicity of Therapeutic Cargo"

Feifei Yang,Yusra Medik,Liantao Li,Xi Tian,Dong Fu,Kim L R Brouwer, Kyle Wangner,Bo Sun,Hossein Sendi,Yu Mi,Andrew Z Wang

Small (Weinheim an der Bergstrasse, Germany)no. 6 (2025): e2405033-e2405033

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Species Dependent Metabolism of a Covalent Nsp2 Protease Inhibitor with in Vivo Anti-alphaviral Activity

Mohammad Anwar Hossain, Abigail K Mayo, Anirban Ghoshal,Sharon Taft-Benz,Elizabeth Anderson, Noah L Morales,Katia D Pressey,Ava Vargason,Kim L R Brouwer,Nathaniel J Moorman,Mark T Heise,Timothy M Willson

Journal of medicinal chemistryno. 10 (2025): 10473-10485

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Impact of Donor Diversity on Phase I and Phase II Activities in Cryopreserved Human Hepatocytes and Human Liver Microsomes

Christopher Bohl,Kenneth Brouwer,Scott Heyward,Karissa Cottier, Courtney Noah,Brian Ogilvie

DRUG METABOLISM AND PHARMACOKINETICS (2024)

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Physiologically Based Pharmacokinetic (PBPK) Model Predictions of Disease Mediated Changes in Drug Disposition in Patients with Nonalcoholic Fatty Liver Disease (NAFLD)

Jeffry Adiwidjaja,Jessica Spires,Kim L. R. Brouwer

Pharmaceutical Research（2024）

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Placental Barrier Transport: Identification of Maternal and Infant Determinants of BCRP and MDR1 Transporter Levels

Lauren Aleksunes,Ranran Zhang,Kylie Getz,John Fallon,Rani Qasem, Jacqueline Tiley,Philip Smith,Kim Brouwer,Jessica Brunner,Richard Miller,Thomas O'Connor,Amber Kautz,Xing Qiu,Dan Dongeun Huh, Hao Zhu,Nicholas Illsley,Pamela Ohman-Strickland,Emily Barrett

PLACENTA (2024): E34-E34

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Alterations in Zonal Distribution and Plasma Membrane Localization of Hepatocyte Bile Acid Transporters in Patients with NAFLD

William A. Murphy,Anna Mae Diehl,Matthew Shane Loop,Dong Fu,Cynthia D. Guy,Manal F. Abdelmalek,Georgia Sofia Karachaliou,Noora Sjostedt,Sibylle Neuhoff,Paavo Honkakoski,Kim L. R. Brouwer

HEPATOLOGY COMMUNICATIONS（2024）

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Hepatic OATP1B Zonal Distribution: Implications for Rifampicin‐mediated Drug–drug Interactions Explored Within a PBPK Framework

Mattie Hartauer,William A. Murphy,Kim L. R. Brouwer, Roz Southall,Sibylle Neuhoff

CPT Pharmacometrics & Systems Pharmacology (2024)

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Altered Bile Acid and Coproporphyrin-I Disposition in Patients with Autosomal Dominant Polycystic Kidney Disease

Jacqueline B. Tiley,James J. Beaudoin, Vimal K. Derebail,William A. Murphy, Christine C. Park, Justin A. Veeder, Lana Tran, Jessica L. Beers,Wei Jia,Paul W. Stewart,Kim L. R. Brouwer

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2024)

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Effects of PFAS on Human Liver Transporters: Implications for Health Outcomes

Ena Vujic,Stephen S. Ferguson,Kim L. R. Brouwer

Toxicological Sciences (2024)

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论文共 388 篇作者统计合作学者相似作者