Jonathan R Brestoff

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个人简介

My lab is focused on understanding how immune cells in white, beige, and brown adipose tissue regulate metabolic adaptation to nutrient stress and the pathogenesis of metabolic diseases such as obesity and type 2 diabetes.

研究兴趣

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Recommendations for Mitochondria Transfer and Transplantation Nomenclature and Characterization

Jonathan R. Brestoff,Keshav K. Singh,Katia Aquilano,Lance B. Becker,Michael V. Berridge, Eric Boilard,Andrés Caicedo,Clair Crewe,José Antonio Enríquez,Jianqing Gao, Åsa B. Gustafsson,Kazuhide Hayakawa,Maroun Khoury,Yun-Sil Lee,Daniele Lettieri-Barbato,Patricia Luz-Crawford, Heidi M. McBride,James D. McCully,Ritsuko Nakai,Jiri Neuzil,Martin Picard,Alexander G. Rabchevsky,Anne-Marie Rodriguez, Shiladitya Sengupta,Alexander J. Sercel, Toshio Suda,Michael A. Teitell, Alain R. Thierry,Rong Tian,Melanie Walker,Minghao Zheng

Nature metabolismno. 1 (2025): 53-67

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SLIT2 is a Novel Driver of Doxorubicin Cardiotoxicity Through Adipose-Cardiac Crosstalk

Mualla Ozcan,Aynaz Lotfinaghsh,Carla Valenzuela Ripoll,Ahmed Diab,Zhen Guo, Wentong Jia, Anahita Ataran, Hamidreza Hajirezaei,Lauren Pedersen,Alireza Sargazi,Babak Razani, Weining Lu,Aarti Asnani,Julio Chirinos,Carmen Bergom,Irfan Lodhi,Jonathan Brestoff,Bettina Mittendorfer,Ali Javaheri

CIRCULATION (2024)

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Lipid-associated Macrophages Reshape BAT Cell Identity in Obesity

Cell reportsno. 7 (2024): 114447-114447

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Brown Fat Fuels the Fire in Fever

Samantha J. Krysa,Jonathan R. Brestoff

Journal of lipid researchno. 11 (2024): 100658-100658

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Mitochondria Transfer-Based Therapies Reduce the Morbidity and Mortality of Leigh Syndrome

Ritsuko Nakai, Stella Varnum,Rachael L. Field,Henyun Shi,Rocky Giwa,Wentong Jia, Samantha J. Krysa, Eva F. Cohen,Nicholas Borcherding,Russell P. Saneto, Rick C. Tsai, Masashi Suganuma, Hisashi Ohta,Takafumi Yokota,Jonathan R. Brestoff

Nature Metabolism (2024)

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Cardiac Troponin to Adjudicate Subclinical Heart Failure in Diabetic Patients and a Murine Model of Metabolic Syndrome

Hannah M. Brown,Nicholas C. Spies,Wentong Jia,John Moley, Sydney Lawless, Brittany Roemmich,Jonathan R. Brestoff,Mark A. Zaydman,Christopher W. Farnsworth

The Journal of Applied Laboratory Medicine (2024)

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Adipocyte Lipin 1 Expression Associates with Human Metabolic Health and Regulates Systemic Metabolism in Mice

Andrew LaPoint,Jason M Singer,Daniel Ferguson,Trevor M Shew,M Katie Renkemeyer,Hector H Palacios,Rachael L Field, Sireesha Yerrathota,Roshan Kumari,Mahalakshmi Shankaran,Gordon I Smith,Jun Yoshino,Mai He,Gary J Patti,Marc K Hellerstein,Samuel Klein,Jonathan R Brestoff,E Matthew Morris,Brian N Finck,Andrew J Lutkewitte

The Journal of clinical investigationno. 23 (2024)

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Distinct Roles for LTalpha3 and LTalpha1beta2 Produced by B Cells Contribute to Their Multi-Faceted Impact on Ileitis

Gwendalyn Randolph,Emma Erlich,Rafael Czepielewski,Rachael Field, Taylor Dunning,Leila Saleh,Mark Hoofnagle, Alexei Tumanov,Farshid Guilak,Jonathan Brestoff

Research square (2024)

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MXRA8 Promotes Adipose Tissue Whitening to Drive Obesity

Wentong Jia,Rocky Giwa,John R. Moley,Gordon I. Smith,Max C. Petersen,Rachael L Field, Omar Abousaway,Arthur S. Kim, Sarah R. Coffey, Stella Varnum, Jasmine M. Wright,Xinya Zhang, Samantha Krysa,Irfan J. Lodhi,Nada A. Abumrad,Samuel Klein,Michael S. Diamond,Jonathan R. Brestoff

biorxiv（2024）

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Burning Fat to Fuel EVs

Clair Crewe,Jonathan R. Brestoff

Diabetesno. 11 (2023): 1521-1523

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论文共 105 篇作者统计合作学者相似作者