My primary research interests are in methodological problems and issues in aging, clinical biostatistics, and bioinformatics. I serve as the lead statistician for the NCI Designated Mays Cancer Center, the Biostatistics Epidemiology and Research Design core within the Institute for the Integration of Medicine and Sciences, Barshop Institute for Longevity and Aging Studies and am the core leader of the Biostatistics and Data Management core of a Claude Pepper Older Americans Independence Center (OAIC). Though trained in statistical genomics, I have expanded my skills to the analysis of clinical trials including behavioral studies. I have served as the lead statistician on four clinical trials related to prostate cancer, clinical dentistry, and diabetes. Additionally, I have served as the lead statistician on a recently completed three-year interventional study of the effects of an educational intervention on teen sexual activity and pregnancy. I have both original methodological papers in Bayesian genomic analysis and collaborative study articles on gene expression analyses. I have extensive experience in the design and analysis of both bench (in vivo, in vitro, and high-throughput expression studies) and clinical research studies as a statistical collaborator on numerous projects that led to over 100 publications.