Dr. Tsai is an aquatic ecotoxicologist and limnologist. He has been involved in teaching and researching freshwater ecology and ecotoxicology by using field/laboratory investigations and mechanistic modeling techniques. His researches center around (1) influence of natural/anthropogenic disturbances on the function of freshwater ecosystems (carbon and nutrient cycling); (2) transportation, bioavailability and trophic transfer of xenobiotics under changing environment, and (3) exposure risk assessment on the health of aquatic species and ecosystems from subcellular to ecosystem level.