Isabel Jaco - Telomeres and Telomerase Group, Spanish National Cancer Center

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论文共 24 篇作者统计合作学者相似作者

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Discovery of WRN Inhibitor HRO761 with Synthetic Lethality in MSI Cancers

Stephane Ferretti,Jacques Hamon,Ruben de Kanter,Clemens Scheufler,Rita Andraos-Rey,Stephanie Barbe,Elisabeth Bechter,Jutta Blank,Vincent Bordas,Ernesta Dammassa, Andrea Decker,Noemi Di Nanni, Marion Dourdoigne, Elena Gavioli,Marc Hattenberger, Alisa Heuser,Christelle Hemmerlin, Juergen Hinrichs,Grainne Kerr,Laurent Laborde,Isabel Jaco,Eloisa Jimenez Nunez,Hans-Joerg Martus,Cornelia Quadt,Markus Reschke,Vincent Romanet, Fanny Schaeffer,Joseph Schoepfer,Maxime Schrapp,Ross Strang,Hans Voshol,Markus Wartmann, Sarah Welly,Frederic Zecri,Francesco Hofmann,Henrik Moebitz,Marta Cortes-Cros

NATURE（2024）

引用12浏览0WOSNATURE引用

Abstract B143: HRO761, a First-in-class, Clinical Stage WRN Inhibitor with Potent Preclinical Anti-Tumor Activity in MSIhigh Models

Stephane Ferretti,Isabel Jaco, Andrea Decker,Christelle Hemmerlin,Clemens Scheufler,Cornelia Quadt,Dario Sterker, Elena Gavioli,Eloisa Jimenez Nunez,Ernesta Dammassa, Fanny Schaeffer,Genevieve Albrecht,Giorgia Clementi,Hansjoerg Martus,Jacques Hamon, Juergen Hinrichs,Laurent Laborde, Marion Dourdoigne, Michele Moschetta, Ramona Stump,Rita Andraos-Rey, Sarah Welly,Stephanie Barbe,Vincent Romanet,Markus Reschke,Ruben De Kanter,Michael Jensen,Henrik Moebitz,Marta Cortes Cros

Molecular Cancer Therapeuticsno. 12_Supplement (2023)

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Abstract PR007: Discovery of HRO761, a Novel, First-in-class Clinical Stage WRN Inhibitor with Potent and Selective Anti-Tumor Activity in Cancers with Microsatellite Instability

Marta Cortes-Cros,Henrik Moebitz,Stephanie Barbe,Jutta Blank,Vincent Bordas,Giorgia Clementi,Ernesta Dammassa, Andrea Decker,Noemi Di Nanni,Ruben de Kanter, Marion Dourdoigne, Elena Gavioli,Stephane Ferretti,Marc Hattenberger,Christelle Hemmerlin,Jacques Hamon, Juergen Hinrichs,Isabel Jaco, Dragana Jankovic,Eloisa Jimenez Nunez, Yifang Li,Hans-Joerg Martus, Michele Moschetta,Cornelia Quadt,Markus Reschke,Vincent Romanet,Clemens Scheufler,Joseph Schoepfer,Ross Strang, Maxime Therier,Hans Voshol,Markus Wartmann, Sarah Welly, Monica Pham,Laurent Laborde

Molecular Cancer Therapeutics（2023）

引用1浏览0引用

Discovery of HRO761, a Novel, First-in-class Clinical Stage WRN Inhibitor with Potent and Selective Anti-Tumor Activity in Cancers with Microsatellite Instability

MOLECULAR CANCER THERAPEUTICSno. 12 (2023)

引用0浏览0引用

The Anticonvulsive Phenhydan® Suppresses Extrinsic Cell Death

Caroline Moerke,Isabel Jaco,Christin Dewitz,Tammo Müller,Annette V. Jacobsen,Jérémie Gautheron,Jürgen Fritsch,Jessica Schmitz,Jan Hinrich Bräsen,Claudia Günther,James M. Murphy,Ulrich Kunzendorf,Pascal Meier,Stefan Krautwald

Cell Death & Differentiation（2018）

引用28浏览0WOSNATURE引用

SUMO-mediated Regulation of NLRP3 Modulates Inflammasome Activity

Rachael Barry,Sidonie Wicky John,Gianmaria Liccardi,Tencho Tenev,Isabel Jaco,Chih-Hong Chen,Justin Choi,Paulina Kasperkiewicz,Teresa Fernandes-Alnemri,Emad Alnemri,Marcin Drag,Yuan Chen,Pascal Meier

Nature Communications（2018）

引用188浏览0WOSNATURE引用

188

MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death

Isabel Jaco,Alessandro Annibaldi,Najoua Lalaoui,Rebecca Wilson,Tencho Tenev,Lucie Laurien,Chun Kim,Kunzah Jamal,Sidonie Wicky John,Gianmaria Liccardi,Diep Chau,James M. Murphy,Gabriela Brumatti,Rebecca Feltham,Manolis Pasparakis,John Silke,Pascal Meier

Molecular Cellno. 5 (2017): 698-710.e5

引用252浏览0WOS引用

252

288 Synthetic Lethality in ERCC1-deficient Non-Small Cell Lung Cancer

S. Postel-Vinay,I. Bajrami,L. Friboulet,I. Jaco,Y. Fontebasso,K. A. Olaussen,J. C. Soria,F. Andre,C. J. Lord,A. Ashworth

EUROPEAN JOURNAL OF CANCER（2012）

引用0浏览0引用

Direct Comparison of Recombination Events at Centromeres and Telomeres Per Kilobase Relative to Global SCE Events in Kilobase in Wild-Type and Deficient ES Cells

Isabel Jaco,Canela Andrés,Vera Elsa,Blasco Maria A.

Figshare (2011)

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