I have a broad background in biomedical engineering with specific training and expertise in bio-photonics, which is essential to accomplish the proposed tasks. I have led a team of graduate students and research staffs at the University of Kentucky (UK) to work continually on technology development and clinical translation of nearinfrared diffuse optical technologies. I have continually played a leading role in multiple collaborative projects supported by federal sponsors and national foundations including National Institutes of Health (NIH), National Science Foundation (NSF), Department of Defense (DOD), American Heart Association (AHA), and National Plastic Surgery Foundation. Through these interdisciplinary studies, my group has established a rich portfolio of collaborations across engineering and medicine.