Dirk does research in Cell Biology, Molecular Biology and Cancer Research.
Research:
In close collaboration with clinicians we're in­ves­ti­ga­ting aberrantly activated signaling cues in cancer with the final goal to find new con­cepts for therapeutic intervention in malignant diseases.
To this aim we're applying state-of-the-art cell bi­o­log­i­cal and biochemical methods and an­a­lyse potential drug targets in murine tumor models.
Spatial intracellular signalling of oncogenic cytokine receptors.
We currently analyse if aberrant localisation of active cytokine receptors is responsible for downstream signal quality und subsequent oncogenic processes.
The role of ADAM-proteases in liver pathologies.
The impact of ADAM-proteases and its regulators on the metastatic process.