During the outbreak of SARS in 2003, Professor Hui worked tirelessly on the frontline at the Prince of Wales Hospital and was heavily involved in the treatment, research and clinical management of patients with the disease. Professor Hui joined the World Health Organization (WHO) in 2004 as an advisor on a specific influenza A (H5N1) outbreak. He has since been a regular advisor to the WHO on the clinical management of severe acute respiratory infections, making valuable contributions to its treatment guidelines and training workshops. Professor Hui served as an advisor to the HKSAR government on COVID-19 between 2020 and 2023.
Since 2019, Professor Hui has been the Chairman of the Scientific Committee on Emerging and Zoonotic Diseases of Hong Kong’s Centre for Health Protection, which is tasked to tackle diseases that could spread from animal hosts to humans.
Professor Hui has published over 450 peer-reviewed journal articles. In 2021 and 2022, he was one of the top 1% of highly cited researchers worldwide, as assessed by Clarivate.