In the Nosanchuk Lab we study a variety of pathogenic fungi and their interactions with the host. We are interested in the mechanisms by which pathogenic fungi cause disease, and how the host reacts when challenged with them. Among the disease-promoting mechanisms employed by fungi, we have a particular interest in extracellular vesicles (EVs) released by these cells, and how they impact the immune response. Our experience shows that the release of EVs by each fungal organism elicits a distinct response in the host that range from stimulation to suppression.