Craig A Emter - Department of Integrative Physiology;University of Colorado;Department of Integrative Physiology, University of Colorado

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Bio

The focus of my research is to understand the impact of novel pharmaceutical and exercise therapeutics on the myocardium and coronary arteries of the failing heart. Current research goals include elucidating new ways to treat both heart failure with preserved ejection fraction (HFpEF; a disease largely unresponsive to current standardized heart failure therapies) and heart failure with reduced ejection fraction (HFrEF) using pre-clinical swine models of heart failure.

Research Interests

Papers共 100 篇Author StatisticsCo-AuthorSimilar Experts

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Chronic Administration of EDG-7500, a Novel Sarcomere Modulator, Prevents Increases in Cardiac Mass, T1 Relaxation Time, and Left Ventricular End Diastolic Pressure in a Yucatan Mini-Pig Model of Genetic Non-Obstructive Hypertrophic Cardiomyopathy

Craig Emter,Sarah Lehman, Lindsey Lee, Emy DiNatale,Angela Peter,Marcus Henze,David Bluemke,Darla Tharp,Steve Roof,Carlos del Rio,Marc Semigran,Alan Russell,Marc Evanchik

CIRCULATION (2024)

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Acute Administration of the Novel Cardiac Sarcomere Modulator EDG-7500, Improves Ventricular Filling While Preserving LVEF in Dogs with Pacing Induced Left-Ventricular Systolic Dysfunction

Marc Evanchik,Craig Emter,Carlos Del Rio,Steve Roof, Sydney St Clair,Alan Russell,Marcus Henze,Marc Semigran

CIRCULATION RESEARCH（2024）

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CHRONIC TREATMENT WITH THE NOVEL SARCOMERE MODULATOR EDG-7500 IMPROVES LEFT VENTRICULAR DISTENSIBILITY AND CARDIAC OUTPUT RECRUITMENT UNDER STRESS IN A MINIPIG GENETIC MODEL OF NON-OBSTRUCTED HYPERTROPHIC CARDIOMYOPATHY

Marc Evanchik,Craig Emter,Carlos L. del Rio, Emily Dinatale,Marcus Henze,Steve Roof, Sydney St Clair, Lindsey Lee,Angela Peter,Alan Russell, Marc J. Semigran

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGYno. 13 (2024): 365-365

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Abstract We094: Acute Administration of the Novel Cardiac Sarcomere Modulator EDG-7500, Improves Ventricular Filling While Preserving LVEF in Dogs with Pacing Induced Left-Ventricular Systolic Dysfunction

Marc Evanchik,Craig Emter,carlos Del Rio,Steve Roof, Sydney St Clair,Alan Russell,Marcus Henze,marc Semigran

Circulation Researchno. Suppl_1 (2024)

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EDG-7500, a Novel Cardiac Sarcomere Regulator That Preserves Intrinsic Myosin-Motor Function, Improves Cardiac Function and Reserve in a Minipig Model of Hypertrophic Cardiomyopathy

Carlos L. Del Rio,Cassady Rupert, Jessica Tolley,Mike Duvall,Craig Emter, Emy DiNatale, Natalie Hawryluk,Alan Russell,Marc Semigran,Marc Evanchik

CIRCULATION（2023）

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Cardiovascular Sex-Differences: Insights Via Physiology-Based Modeling and Potential for Noninvasive Sensing Via Ballistocardiography

Mohamed Zaid,Lorenzo Sala,Laurel Despins,David Heise,Mihail Popescu,Marjorie Skubic,Salman Ahmad,Craig A. Emter,Virginia H. Huxley,Giovanna Guidoboni

FRONTIERS IN CARDIOVASCULAR MEDICINE（2023）

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Sex and Diet, but Not Exercise, Alter Cardiovascular ACE2 and TMPRSS2 Mrna Levels in Aortic Banded Swine

Shannon C. Kelly,Pamela K. Thorne,Emily V. Leary,Craig A. Emter

Journal of Applied Physiology（2023）

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Impact of Sex and Diet-Induced Weight Loss on Vascular Insulin Sensitivity in Type 2 Diabetes

Camila Manrique-Acevedo,Rogerio N. Soares,James A. Smith,Lauren K. Park,Katherine Burr,Francisco I. Ramirez-Perez,Neil J. McMillan,Larissa Ferreira-Santos,Neekun Sharma,T. Dylan Olver,Craig A. Emter,Elizabeth J. Parks,Jacqueline K. Limberg,Luis A. Martinez-Lemus,Jaume Padilla

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY（2023）

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Decreased Arterial Elastance Following a Novel RSK3/mAKAPß Gene Therapy is Associated with Improved Bradykinin-Dependent Pial Artery Dilation in Aortic-Banded, Western Diet-Fed Female Ossabaw Swine

Darla Tharp,Amira Amin,Pamela Thorne,Christina Mueller,Jinliang Li,T. Dylan Olver,Michael Kapiloff,Craig Emter

PHYSIOLOGY（2023）

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A Novel RSK3/mAKAPß Signalosome-Focused Gene Therapy Inhibits Developing Heart Failure in Aortic-Banded, Western Diet-Fed Female Ossabaw Swine

Darla Tharp,Jinliang Li,Amira Amin,Pamela Thorne,Christina Mueller,Federico Cividini,Michael Kapiloff,Craig Emter

PHYSIOLOGY（2023）

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