Lamb Christopher A

I am an Honorary Consultant Gastroenterologist at the Newcastle upon Tyne Hospitals NHS Foundation Trust and a Principal Investigator in the Translational & Clinical Research Institute at Newcastle University. I have a specialist interest in Crohn's disease and ulcerative colitis, the two principle forms of inflammatory bowel disease (IBD) and my research focuses on therapeutics, in particular precision medicine. I study the intestinal immune system, how this maintains health or can drive inflammation, and how our immune system interacts with, and is shaped by gut microbiota (bacteria, viruses and fungi). A previous Wellcome Trust Clinical Fellow in Translational Medicine and Therapeutics and an NIHR Clinical Lecturer, I am now the Chief Investigator for the national IBD-RESPONSE and CD-metaRESPONSE studies funded by the Medical Research Council and the Helmsley Charitable Trust which will use multi-omic data (microbiome, metabolome, genome, single cell transcriptome, diet) and machine learning to develop a predictive model of response to advanced therapies (biologics and small molecules) in IBD. I am the lead author of the British Society of Gastroenterology guidelines for the management of IBD and the co-lead author for the joint British Society of Gastroenterology and British Society of Paediatric Gastroenterology Hepatology and Nutrition guideline for diagnosis and care coordination of monogenic IBD. I work closely with the patient representative body Crohn's & Colitis UK and sit on the Steering Committee of IBD UK to contribute to national qualitative improvement research and clinical implementation in IBD care. I am the current Secretary of the British Society of Gastroenterology Inflammatory Bowel Disease Section. I have recently received a United European Gastroenterology Rising Star 2023 award.