At the NCAA, Brian developed, in partnership with the Department of Defense, the NCAA-DoD Grand Alliance CARE Consortium, which is a $100+ million study whose aim is to understand the natural history of concussion neurobiological recovery in concussion and repetitive head impact exposure. The clinical study, with an advanced research component, is the largest, prospective clinical study ever conducted in the history of concussion. The Grand Alliance also includes a Mind Matters educational and research initiative, whose goal is to change the culture of concussion. Brian has taken a leadership role in addressing other pressing issues of student-athletes, including mental health, overuse injuries, alcohol and drug abuse, sexual violence, and sudden cardiac death. Through a collaborative effort with key medical organizations, Brian has spear-headed task forces that have led to inter-association documents on concussion, independent medical care, year-round football practice contact, mental health, cardiovascular care, catastrophic injury and sexual violence. He has also developed key alliances with youth sport organizations, understanding that an effective sport model begins at youth and extends to college and beyond, with a premise that sport should be a model of wellness for life. He served as co-chair of two International Olympic Committee summits: Pain Medicine in Elite Athletes; and Mental Health and Elite Athletes, both of which produced primary consensus papers and numerous sub-specialty papers.