Benjamin Primack - 1Obsidian Therapeutics

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Papers共 23 篇Author StatisticsCo-AuthorSimilar Experts

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IL-2-independent Expansion, Persistence, and Antitumor Activity in TIL Expressing Regulatable Membrane-Bound IL-15

Rachel A Burga, Bulent Arman Aksoy,Zheng Ao, Jeremy H Tchaicha,Dhruv K Sethi, Alonso Villasmil Ocando, Gauri S Kulkarni, Scott Lajoie,Kyle D Pedro, Jack Ryan Tremblay, Meghan Langley,Benjamin Primack, Violet A Young, Theresa Ross,Mithun Khattar, Dexue Sun, Dan Jun Li,Shyam Subramanian,Michelle Ols,Jan Ter Meulen

Molecular therapy the journal of the American Society of Gene Therapy (2025)

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Carbonic Anhydrase 2-Derived Drug-Responsive Domain Regulates Membrane-Bound Cytokine Expression and Function in Engineered T Cells

Mara C. Inniss, Sean G. Smith, Dan Jun Li,Benjamin Primack, Dexue Sun, Grace Y. Olinger, Kerri-Lynn Sheahan,Theresa Ross,Meghan Langley,Violet Young, Andres Alvarado, Shabnam Davoodi, Jiefei Geng,Michael Schebesta, Michelle L. Ols,Jeremy Tchaicha,Jan ter Meulen,Dhruv K. Sethi

Communications Biologyno. 1 (2025): 1-16

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457 Engineered Tumor-Infiltrating Lymphocytes (TIL) with Co-Regulated Membrane-Bound IL15 (mbil15) and LIGHT (TNFSF14) Generate Significant Antitumor Efficacy in Fibrotic Tumor Models

Benjamin Primack,Balazs Koscso,Violet Young,Meghan Langley,Theresa Ross, Ngoc Ly,Carmela Passaro,Zheng Ao, Sean G Smith,Nirzari Shah,Dexue Sun,Dan Jun Li,Dhruv K Sethi,Jan ter Meulen,Michelle Ols,Jeremy Tchaicha

Regular and Young Investigator Award Abstracts (2024)

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Abstract LB065: Tumor-infiltrating Lymphocytes (TIL) Engineered with Regulatable Membrane-Bound IL15 (mbil15) and LIGHT (TNFSF14) Show Enhanced Efficacy in Fibroblast-Containing Cold Tumors

Balazs Koscso,Zheng Ao,Carmela Passaro,Nirzari Shah,Ngoc Ly,Patricia Timpug, Bulent A. Aksoy,Dexue Sun,Dan Jun Li, Kerri-Lynn Sheahan,Violet Young,Theresa Ross,Benjamin Primack,Meghan Langley,Jeremy Tchaicha,Dhruv K. Sethi,Jan ter Meulen,Michelle Ols

CANCER RESEARCH（2024）

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463 Antigen-responsive Promoters Coupled with Cytodrive®technology Provide Tight Spatiotemporal Regulation for Tumor-Infiltrating Lymphocytes (TIL) Expressing Membrane-Bound IL12

Sean G Smith,Meghan Langley,Theresa Ross,Patricia Timpug,Dexue Sun, Alonso Ocando,Zheng Ao,Balazs Koscso,Benjamin Primack,Violet Young,Dhruv K Sethi,Jeremy Tchaicha,Jan ter Meulen,Michelle Ols

Regular and Young Investigator Award Abstracts (2024)

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348 TIL Engineered with Membrane-Bound IL15 (cytotil15™) Are Enriched for Tumor-Associated Antigen Reactivity and Demonstrate Pharmacologically Tunable Expansion and Persistence in the Presence of TAA

Kyle Pedro,Alonso Villasmil Ocando,Benjamin Primack,Meghan Langley,Theresa Ross,Jeremy Tchaicha,Michelle Ols,Jan ter Meulen,Violet Young,Gauri Kulkarni, Arman Aksoy,Rachel A Burga

Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)

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IL15-engineered Tumor Infiltrating Lymphocytes (cytotil15™) Exhibit Activity Against Autologous Tumor Cells from Multiple Solid Tumor Indications Without IL2

Kyle D. Pedro,Rachel Burga,Alonso Villasmil Ocando,Meghan Langley,Gauri Kulkarni,Zheng Ao,Benjamin Primack,Theresa Ross,Violet Young,Jeremy Tchaicha,Michelle Ols,Jan Ter Meulen

CANCER RESEARCHno. 8 (2023)

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Abstract LB096: IL15-engineered Tumor Infiltrating Lymphocytes (cytotil15tm) Exhibit Activity Against Autologous Tumor Cells from Multiple Solid Tumor Indications Without IL2

Kyle D. Pedro,Rachel Burga,Alonso Villasmil Ocando,Meghan Langley,Gauri Kulkarni,Zheng Ao,Benjamin Primack,Theresa Ross,Violet Young,Jeremy Tchaicha,Michelle Ols,Jan Ter Meulen

Cancer Research（2023）

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278 Pharmacologically-controlled Expression of Membrane-Bound IL-12 Results in T-cell Therapy with Enhanced Potency in Preclinical Solid Tumor Models

Sean Smith,Benjamin Primack,Theresa Ross,Patricia Timpug,Dexue Sun,Dan Jun Li,Scott Lajoie,Violet Young,Meghan Langley,Jeremy Tchaicha,Dhruv Sethi,Jan ter Meulen,Michelle Ols

Regular and Young Investigator Award Abstracts (2022)

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Abstract LB101: Novel Drug-responsive Domain (Drd)-Based Regulation Technology Enables Tightly Controlled Activity of Potent Membrane-Bound IL12 in Adoptive Cell Therapies

Sean Gregory Smith, James A. Storer,Dexue Sun,Dan Jun Li,Benjamin Primack,Theresa Ross,Scott LaJoie,Jeremy Tchaicha,Dhruv Sethi,Jan ter Meulen,Michelle Ols

Cancer Researchno. 12_Supplement (2022)

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