Annemette Thougaard - Lundbeck | 人才画像

基本信息

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Bio

Annemette Thougaard currently works at the Department of Exploratory Toxicology, Lundbeck. We work with in vitro and in vivo exploratory and mechanistic toxicology for compounds in the discovery and preclinical phase. The most recent publication is 'PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats'.

Research Interests

Papers共 42 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Supplemental Table S2 from Activity of PXD101, a Histone Deacetylase Inhibitor, in Preclinical Ovarian Cancer Studies

Xiaozhong Qian,William J. LaRochelle,Gulshan Ara,Frank Wu,Kamille Dumong Petersen,Annemette Thougaard,Maxwell Sehested,Henri S. Lichenstein,Michael Jeffers

openalex（2023）

Cited0Views0Bibtex

Nonclinical Safety Evaluation, Pharmacokinetics, and Target Engagement of Lu AF82422, a Monoclonal IgG1 Antibody Against Alpha-Synuclein in Development for Treatment of Synucleinopathies

Lone Fjord-Larsen,Annemette Thougaard,Karen Malene Wegener,Joan Christiansen,Frank Larsen, Lise Maj Schroder-Hansen, Marianne Kaarde,Dorte Kornerup Ditlevsen

mAbs（2021）

Cited18Views0WOSBibtex

Predicting the Safety of Drug Targets

Jennifer Venhorst,Lars Verschuren,Annemette Thougaard,Jorrit J. Hornberg,Tanja Rouhani Rankouhi

Chapman and Hall/CRC eBookspp.74-86, (2019)

Cited0Views0Bibtex

Predicting The Safety Of Drug Targets An In Silico Perspective

Jennifer Venhorst,Lars Verschuren,Annemette V. Thougaard,Jorrit J. Hornberg,Tanja Rouhani Rankouhi

HANDBOOK OF BIOMARKERS AND PRECISION MEDICINEpp.74-86, (2019)

Cited1Views0Bibtex

PFE-360-induced LRRK2 Inhibition Induces Reversible, Non-Adverse Renal Changes in Rats

Michael Aagaard Andersen,Karen Malene Wegener,Steen Larsen,Lassina Badolo,Garrick Paul Smith,Ross Jeggo,Poul Henning Jensen,Florence Sotty,Kenneth Vielsted Christensen,Annemette Thougaard

Toxicology (2018): 15-22

Cited47Views0WOSBibtex

Linking HSP90 Target Occupancy to HSP70 Induction and Efficacy in Mouse Brain

Kenneth Thirstrup,Florence Sotty,Liliana Christina Pereira Montezinho,Lassina Badolo,Annemette Thougaard, Maj Kristjansson,Thomas Jensen,Stephen Watson,Soren Moller Nielsen

Pharmacological Research（2015）

Cited19Views0WOSBibtex

Validation of a High Throughput Flow Cytometric in Vitro Micronucleus Assay Including Assessment of Metabolic Activation in TK6 Cells

Annemette V. Thougaard,Joan Christiansen,Tomas Mow,Jorrit J. Hornberg

Environmental and Molecular Mutagenesis（2014）

Cited19Views0WOSBibtex

Exploratory Toxicology As an Integrated Part of Drug Discovery. Part I: Why and How

Jorrit J. Hornberg,Morten Laursen,Nina Brenden,Mikael Persson,Annemette V. Thougaard,Dorthe B. Toft,Tomas Mow

DRUG DISCOVERY TODAY（2014）

Cited85Views0WOSBibtex

Validation of the flow cytometry micronucleus assay in TK6 cells with assessment of metabolic activation in 96-well format

Annemette V. Thougaard,Joan Christiansen,Tomas Mow,Jorrit J. Hornberg

MUTAGENESISno. 6 (2014): 559-559

Cited0Views0Bibtex

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