Andy’s main research specialism is Neurophysiology. This means he works on gaining greater understandings of the electrical signaling which conveys information within the circuits of the mammalian CNS. His team also tries to understand how these signals encode the information that the CNS requires to perform its multifaceted functions, from sensory detection through to learning and memory.
His team employs a range of methods using microelectrodes to directly measure or evoke electrical activity alongside real time optically-based methods such as multiphoton imaging.
Andy has interests in a number of diseases that impact upon electrical signaling in the brain, with a particular current focus on Alzheimer’s disease and other dementias. He has also worked on experimental investigations related to schizophrenia, epilepsy and pain.