Alexander M. Efanov - Lilly Research Laboratories, Eli Lilly and Company

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Aggregated Proinsulin in Pancreatic Β-Cells is Degraded by the Autophagy Pathway

Yueh-Fu Madey,Samreen K. Syed, Robert Daniel Van Horn,Annie R. Pineros,Alexander M. Efanov

Journal of Biological Chemistrypp.108257, (2025)

引用0浏览0WOS引用

401.5: Shielded Living Therapeutics Platform for the Treatment of Type 1 Diabetes

Olivia Kelly,P. Mason McClatchey,Mandar Bawadekar, Jillian Higgins,Kathleen Barrett,Matthew Buchanan, Christopher Sparages, Aviv Preminger, Daniel Fraher, Tristan Lawson,Paul Nguyen,Jamie Kady,Catherine Kooyomjian,Alexander M Efanov,Michael Brehm,Melissa K Thomas,Joseph Tumang,Sarah Yuan,Philip G Ashton-Rickardt

Transplantationno. 10S2 (2023): 160-160

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Identification of Biomarkers for Glycaemic Deterioration in Type 2 Diabetes

Roderick C. Slieker,Louise A. Donnelly,Elina Akalestou,Livia Lopez-Noriega, Rana Melhem,Ayşim Güneş, Frederic Abou Azar,Alexander Efanov,Eleni Georgiadou,Hermine Muniangi-Muhitu, Mahsa Sheikh,Giuseppe N. Giordano,Mikael Åkerlund,Emma Ahlqvist,Ashfaq Ali,Karina Banasik,Søren Brunak,Marko Barovic,Gerard A. Bouland,Frédéric Burdet,Mickaël Canouil,Iulian Dragan,Petra J. M. Elders,Celine Fernandez,Andreas Festa,Hugo Fitipaldi,Phillippe Froguel,Valborg Gudmundsdottir,Vilmundur Gudnason,Mathias J. Gerl,Amber A. van der Heijden,Lori L. Jennings,Michael K. Hansen,Min Kim,Isabelle Leclerc,Christian Klose,Dmitry Kuznetsov,Dina Mansour Aly,Florence Mehl,Diana Marek,Olle Melander,Anne Niknejad,Filip Ottosson,Imre Pavo,Kevin Duffin,Samreen K. Syed, Janice L. Shaw,Over Cabrera,Timothy J. Pullen,Kai Simons,Michele Solimena,Tommi Suvitaival,Asger Wretlind,Peter Rossing,Valeriya Lyssenko,Cristina Legido Quigley,Leif Groop,Bernard Thorens,Paul W. Franks,Gareth E. Lim,Jennifer Estall,Mark Ibberson,Joline W. J. Beulens,Leen M ’t Hart,Ewan R. Pearson,Guy A. Rutter

Nature Communicationsno. 1 (2023)

引用18浏览0WOSNATURE引用

Shielded living therapeutics platform for the treatment of type 1 diabetes

Olivia Kelly,P. Mason Mcclatchey,Mandar Bawadekar, Jillian Higgins,Kathleen Barrett,Matthew Buchanan, Christopher Sparages, Aviv Preminger, Daniel Fraher, Tristan Lawson,Paul Nguyen,Jamie Kady,Catherine Kooyomjian,Alexander M. Efanov,Michael Brehm,Melissa K. Thomas,Joseph Tumang,Sarah Yuan,Philip G. Ashton-Rickardt

TRANSPLANTATION（2023）

引用0浏览0引用

BACH2 Inhibition Reverses Β Cell Failure in Type 2 Diabetes Models

Jinsook Son,Hongxu Ding,Thomas B. Farb,Alexander M. Efanov,Jiajun Sun, Julie L. Core,Samreen K. Syed, Zhigang Lei,Qidi Wang,Domenico Accili,Andrea Califano

Journal of Clinical Investigation（2021）

引用45浏览0WOS引用

A High-Throughput Assay for the Pancreatic Islet Beta-Cell Potassium Channel: Use in the Pharmacological Characterization of Insulin Secretagogues Identified from Phenotypic Screening

Luyan Song,David G. Barrett,Karen L. Cox,Alexander M. Efanov,Samreen K. Syed,Dirk Tomandl,Francis S. Willard

Assay and Drug Development Technologies（2020）

引用2浏览0WOS引用

20-OR: GPR142 Agonists Increase Glucose-Dependent Insulin Secretion and Differentially Regulate Hormone Secretion in Preclinical and Phase 1 Studies

Edward J. Pratt,Tomonori Oura,Xiaosu Ma,Hua V. Lin,Tianwei Ma,Alexander M. Efanov,Melissa K. Thomas

DIABETES（2019）

引用6浏览0引用

Long-Acting and Selective Oxytocin Peptide Analogs Show Antidiabetic and Antiobesity Effects in Male Mice

Brandy Snider,Andrea Geiser,Xiao-peng Yu, Emily Cathleen Beebe,Jill Amanda Willency,Keyun Qing, Lili Guo,Jianliang Lu,Xiaojun Wang,Qian Yang,Alexander Efanov,Andrew Charles Adams,Tamer Coskun,Paul Joseph Emmerson,Jorge Alsina-Fernandez,Minrong Ai

Journal of the Endocrine Society（2019）

引用30浏览0WOS引用

Catechol Estrogens Stimulate Insulin Secretion in Pancreatic Β-Cells Via Activation of the Transient Receptor Potential A1 (TRPA1) Channel

Wenzhen Ma,Xingjuan Chen,Rok Cerne,Samreen K. Syed,James V. Ficorilli,Over Cabrera,Alexander G. Obukhov,Alexander M. Efanov

JOURNAL OF BIOLOGICAL CHEMISTRY（2019）

引用19浏览0WOS引用

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